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Medicinos knygos ir literatūra studijoms, mokslui, visuomenei

Žurnalas Medicina volume 55.issue 3. May 2019 (part1,2)

6,35€
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Prekės kodas: 1010-660 may
ISBN: 
1010-660 may
Leidykla: 
LSMU Leidybos namai
Išleista: 
2019
Knygos kalba: 
Anglų
Formatas: 
A4
Viršelis: 
Minkštas
Puslapių: 
1100
Svoris: 2,800 kg

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Visos knygos · Bendroji gydytojo praktika · Žurnalai

Dalintis

     

Persistent pain is a common and significant medical condition with diverse impacts on people’s lives. Codeine phosphate is a regularly prescribed analgesic for moderate to severe pain, and is reliant on biotransformation to morphine by the CYP2D6 enzyme for efficacy. In this study, we investigated the codeine response in Caucasians with persistent pain using CYP2D6 genotyping and urinary metabolite concentrations to develop a biomedical model for predicting long-term codeine responses. This model could aid clinical decision-making when prescribing codeine and improve analgesic responses.

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LSMU KNYGYNAS