Underwoods Pathology (formerly General and Systematic Pathology) is an internationally popular and highly acclaimed textbook, written and designed principally for students of medicine and the related health sciences. Pathology is presented in the context of modern cellular and molecular biology and contemporary clinical practice. After a clear introduction to basic principles, it provides comprehensive coverage of disease mechanisms and the pathology of specific disorders ordered by body system. An unrivalled collection of clinical photographs, histopathology images and graphics complement the clear, concise text. For this seventh edition, the entire book has been revised and updated. Well liked features to assist problem-based learning - including body diagrams annotated with signs, symptoms and diseases and a separate index of common clinical problems - have been retained and refreshed. The advent of whole genome sequencing and increased knowledge of the genetics of disease has been recognised by updated sections in many chapters. Download the enhanced eBook version (from studentconsult.com) for anytime access to the complete contents plus bonus learning materials, including: clinical case studies - to help apply essential principles to modern practice the fully revised, interactive self-assessment section with over 200 questions and answers - to check your understanding and aid exam preparation especially produced video and podcast tutorials - to further explain and bring to life key topics bonus pathology crosswords - to recall key words and topics in a fun and interactive way This all combines to make Underwoods an unsurpassed learning package in this fascinating and most central medical specialty. From reviews of previous editions: ...it truly is an outstanding textbook...highly recommended Histopathology ...no doubt it will remain a bestseller - excellent value for undergraduates Journal of Clinical Pathology A book of this kind deserves a wide readership Modern Pathology .. the definitive textbook of pathology...expands on previous success and cements its position as the market leader for undergraduate pathology The Bulletin A prize winner: Previous editions have won First Prize in the Medical Writers Group of the Society of Authors Awards, the British Book Design and Production Awards and the British Medical Association Student Textbook Award.

Preface vi
Acknowledgements vii
International Advisors viii
Contributors ix
Index of Patient Symptoms x
Get the Most Out of Your Enhanced eBook! xviii
PART 1 BASIC PATHOLOGY

1 What is pathology?
3 (8)
James C. E. Underwood
2 What is disease?
11 (16)
James C. E. Underwood
3 What causes disease?
27 (28)
James C. E. Underwood
Simon S. Cross
PART 2 DISEASE MECHANISMS

4 Disorders of growth, differentiation and morphogenesis
55 (22)
Jonathan Bury
5 Responses to cellular injury
77 (18)
Jonathan Bury
6 Disorders of metabolism and homeostasis
95 (20)
Stephen R. Morley
7 Ischaemia, infarction and shock
115 (12)
Simon S. Cross
8 Immunology and immunopathology
127 (32)
W. A. Carrock Sewell
9 Inflammation
159 (18)
Timothy J. Stephenson
10 Neoplasia and carcinogenesis
177 (42)
Mark J. Arends
11 Ageing and death
219 (10)
Emyr W. Benbow
12 How do pathologists help patient care?
229 (13)
Patricia V. Vergani
PART 3 SYSTEMATIC PATHOLOGY

13 Cardiovascular system
242 (42)
S. Kim Suvarna
14 Respiratory tract
284 (34)
William A. H. Wallace
15 Alimentary system
318 (38)
Heike I. Grabsch
16 Liver, biliary system and pancreas
356 (32)
Judith I. Wyatt
Beate Haugk
17 Endocrine system
388 (28)
Timothy J. Stephenson
18 Breast
416 (22)
J. Louise Jones
19 Female genital tract
438 (28)
Sanjiv Manek
20 Urinary and male genital tracts
466 (28)
Daniel Berney
21 Kidney diseases
494 (30)
Ian S.D. Roberts
22 Lymph nodes and extranodal lymphoid tissue, spleen and thymus
524 (26)
Bridget S. Wilkins
23 Blood and bone marrow
550 (58)
Dominic Culligan
Henry G. Watson
24 Skin
608 (28)
Colin Moyes
Karen Blessing
25 Osteoarticular and connective tissues
636 (34)
David E. Hughes
26 Central and peripheral nervous systems
670 (46)
James W. Ironside
Colin Smith
Glossary 716 (7)
Index 723